1669Genetic Diversity of Pneumolysin and Pneumococcal Histidine Triad Protein D of Streptococcus pneumoniae Isolated from Invasive Infections in Children
نویسندگان
چکیده
Protein D of Streptococcus pneumoniae Isolated from Invasive Infections in Children Ki Wook Yun, MD, PhD; Young June Choe, MD, MPH; In Ae Yoon, MD; Eun Hwa Choi, MD, PhD; Hoan Jong Lee, MD, PhD, FIDSA; Pediatrics, Chung-Ang University College of Medicine, Seoul, South Korea; Pediatrics, Seoul National University College of Medicine, Seoul, South Korea; Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, South Korea; Department of Pediatrics, Seoul National University College of Medicine, Seoul, South Korea
منابع مشابه
Antibodies to PcpA and PhtD protect mice against Streptococcus pneumoniae by a macrophage- and complement-dependent mechanism
Currently marketed Streptococcus pneumoniae (Spn) vaccines, which contain polysaccharide capsular antigens from the most common Spn serotypes, have substantially reduced pneumococcal disease rates but have limited coverage. A trivalent pneumococcal protein vaccine containing pneumococcal choline-binding protein A (PcpA), pneumococcal histidine triad protein D (PhtD), and detoxified pneumolysin ...
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